diff --git a/.cargo/config.toml b/.cargo/config.toml
index 8515f874..84e72904 100644
--- a/.cargo/config.toml
+++ b/.cargo/config.toml
@@ -1,2 +1,2 @@
-[target.'cfg(target_os = "wasi")']
+[target.'cfg(target_family = "wasm")']
 rustflags = ["-C", "target-feature=+atomics,+bulk-memory"]
diff --git a/crates/backend/src/codegen/const.rs b/crates/backend/src/codegen/const.rs
index 8d217571..d58b5041 100644
--- a/crates/backend/src/codegen/const.rs
+++ b/crates/backend/src/codegen/const.rs
@@ -41,7 +41,7 @@ impl NapiConst {
       }
       #[allow(non_snake_case)]
       #[allow(clippy::all)]
-      #[cfg(all(not(test), not(feature = "noop"), not(target_os = "wasi")))]
+      #[cfg(all(not(test), not(feature = "noop"), not(target_family = "wasm")))]
       #[napi::bindgen_prelude::ctor]
       fn #register_name() {
         napi::bindgen_prelude::register_module_export(#js_mod_ident, #js_name_lit, #cb_name);
@@ -49,7 +49,7 @@ impl NapiConst {
 
       #[allow(non_snake_case)]
       #[allow(clippy::all)]
-      #[cfg(all(not(test), not(feature = "noop"), target_os = "wasi"))]
+      #[cfg(all(not(test), not(feature = "noop"), target_family = "wasm"))]
       #[no_mangle]
       unsafe extern "C" fn #register_name() {
         napi::bindgen_prelude::register_module_export(#js_mod_ident, #js_name_lit, #cb_name);
diff --git a/crates/backend/src/codegen/enum.rs b/crates/backend/src/codegen/enum.rs
index 0be465d8..870d1c2f 100644
--- a/crates/backend/src/codegen/enum.rs
+++ b/crates/backend/src/codegen/enum.rs
@@ -158,14 +158,14 @@ impl NapiEnum {
       }
       #[allow(non_snake_case)]
       #[allow(clippy::all)]
-      #[cfg(all(not(test), not(feature = "noop"), not(target_os = "wasi")))]
+      #[cfg(all(not(test), not(feature = "noop"), not(target_family = "wasm")))]
       #[napi::bindgen_prelude::ctor]
       fn #register_name() {
         napi::bindgen_prelude::register_module_export(#js_mod_ident, #js_name_lit, #callback_name);
       }
       #[allow(non_snake_case)]
       #[allow(clippy::all)]
-      #[cfg(all(not(test), not(feature = "noop"), target_os = "wasi"))]
+      #[cfg(all(not(test), not(feature = "noop"), target_family = "wasm"))]
       #[no_mangle]
       extern "C" fn #register_name() {
         napi::bindgen_prelude::register_module_export(#js_mod_ident, #js_name_lit, #callback_name);
diff --git a/crates/backend/src/codegen/fn.rs b/crates/backend/src/codegen/fn.rs
index 0dba1c26..0998d694 100644
--- a/crates/backend/src/codegen/fn.rs
+++ b/crates/backend/src/codegen/fn.rs
@@ -598,7 +598,7 @@ impl NapiFn {
 
         #[allow(clippy::all)]
         #[allow(non_snake_case)]
-        #[cfg(all(not(test), not(feature = "noop"), not(target_os = "wasi")))]
+        #[cfg(all(not(test), not(feature = "noop"), not(target_family = "wasm")))]
         #[napi::bindgen_prelude::ctor]
         fn #module_register_name() {
           napi::bindgen_prelude::register_module_export(#js_mod_ident, #js_name, #cb_name);
@@ -606,7 +606,7 @@ impl NapiFn {
 
         #[allow(clippy::all)]
         #[allow(non_snake_case)]
-        #[cfg(all(not(test), not(feature = "noop"), target_os = "wasi"))]
+        #[cfg(all(not(test), not(feature = "noop"), target_family = "wasm"))]
         #[no_mangle]
         extern "C" fn #module_register_name() {
           napi::bindgen_prelude::register_module_export(#js_mod_ident, #js_name, #cb_name);
diff --git a/crates/backend/src/codegen/struct.rs b/crates/backend/src/codegen/struct.rs
index b39103a0..4ff657eb 100644
--- a/crates/backend/src/codegen/struct.rs
+++ b/crates/backend/src/codegen/struct.rs
@@ -778,7 +778,7 @@ impl NapiStruct {
     quote! {
       #[allow(non_snake_case)]
       #[allow(clippy::all)]
-      #[cfg(all(not(test), not(feature = "noop"), not(target_os = "wasi")))]
+      #[cfg(all(not(test), not(feature = "noop"), not(target_family = "wasm")))]
       #[napi::bindgen_prelude::ctor]
       fn #struct_register_name() {
         napi::__private::register_class(#name_str, #js_mod_ident, #js_name, vec![#(#props),*]);
@@ -786,7 +786,7 @@ impl NapiStruct {
 
       #[allow(non_snake_case)]
       #[allow(clippy::all)]
-      #[cfg(all(not(test), not(feature = "noop"), target_os = "wasi"))]
+      #[cfg(all(not(test), not(feature = "noop"), target_family = "wasm"))]
       #[no_mangle]
       extern "C" fn #struct_register_name() {
         napi::__private::register_class(#name_str, #js_mod_ident, #js_name, vec![#(#props),*]);
@@ -901,13 +901,13 @@ impl NapiImpl {
         use super::*;
         #(#methods)*
 
-        #[cfg(all(not(test), not(feature = "noop"), not(target_os = "wasi")))]
+        #[cfg(all(not(test), not(feature = "noop"), not(target_family = "wasm")))]
         #[napi::bindgen_prelude::ctor]
         fn #register_name() {
           napi::__private::register_class(#name_str, #js_mod_ident, #js_name, vec![#(#props),*]);
         }
 
-        #[cfg(all(not(test), not(feature = "noop"), target_os = "wasi"))]
+        #[cfg(all(not(test), not(feature = "noop"), target_family = "wasm"))]
         #[no_mangle]
         extern "C" fn #register_name() {
           napi::__private::register_class(#name_str, #js_mod_ident, #js_name, vec![#(#props_wasm),*]);
diff --git a/crates/macro/src/lib.rs b/crates/macro/src/lib.rs
index bd7c09bc..30612ffd 100644
--- a/crates/macro/src/lib.rs
+++ b/crates/macro/src/lib.rs
@@ -151,7 +151,7 @@ pub fn module_exports(_attr: TokenStream, input: TokenStream) -> TokenStream {
   };
 
   let register = quote! {
-    #[cfg_attr(not(target_os = "wasi"), napi::bindgen_prelude::ctor)]
+    #[cfg_attr(not(target_family = "wasm"), napi::bindgen_prelude::ctor)]
     fn __napi__explicit_module_register() {
       unsafe fn register(raw_env: napi::sys::napi_env, raw_exports: napi::sys::napi_value) -> napi::Result<()> {
         use napi::{Env, JsObject, NapiValue};
diff --git a/crates/napi/Cargo.toml b/crates/napi/Cargo.toml
index 833b8a45..bebfa7e5 100644
--- a/crates/napi/Cargo.toml
+++ b/crates/napi/Cargo.toml
@@ -75,11 +75,11 @@ version = "0.8"
 optional = true
 version = "0.4"
 
-[target.'cfg(target_os = "wasi")'.dependencies]
+[target.'cfg(target_family = "wasm")'.dependencies]
 napi-derive = { path = "../macro", version = "2.10.1", default-features = false }
 tokio = { version = "1", optional = true, features = ["rt", "sync"] }
 
-[target.'cfg(not(target_os = "wasi"))'.dependencies]
+[target.'cfg(not(target_family = "wasm"))'.dependencies]
 tokio = { version = "1", optional = true, features = [
   "rt",
   "rt-multi-thread",
diff --git a/crates/napi/src/bindgen_runtime/js_values/arraybuffer.rs b/crates/napi/src/bindgen_runtime/js_values/arraybuffer.rs
index 4bbacc12..d3bdde48 100644
--- a/crates/napi/src/bindgen_runtime/js_values/arraybuffer.rs
+++ b/crates/napi/src/bindgen_runtime/js_values/arraybuffer.rs
@@ -7,14 +7,14 @@ use std::sync::{
   Arc,
 };
 
-#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_os = "wasi")))]
+#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_family = "wasm")))]
 use crate::bindgen_prelude::{CUSTOM_GC_TSFN, CUSTOM_GC_TSFN_DESTROYED, THREADS_CAN_ACCESS_ENV};
 pub use crate::js_values::TypedArrayType;
 use crate::{check_status, sys, Error, Result, Status};
 
 use super::{FromNapiValue, ToNapiValue, TypeName, ValidateNapiValue};
 
-#[cfg(target_os = "wasi")]
+#[cfg(target_family = "wasm")]
 extern "C" {
   fn emnapi_sync_memory(
     env: crate::sys::napi_env,
@@ -80,7 +80,7 @@ macro_rules! impl_typed_array {
             if ref_.is_null() {
               return;
             }
-            #[cfg(all(feature = "napi4", not(feature = "noop"), not(target_os = "wasi")))]
+            #[cfg(all(feature = "napi4", not(feature = "noop"), not(target_family = "wasm")))]
             {
               if CUSTOM_GC_TSFN_DESTROYED.load(Ordering::SeqCst) {
                 return;
@@ -140,7 +140,7 @@ macro_rules! impl_typed_array {
     impl $name {
       fn noop_finalize(_data: *mut $rust_type, _length: usize) {}
 
-      #[cfg(target_os = "wasi")]
+      #[cfg(target_family = "wasm")]
       pub fn sync(&mut self, env: &crate::Env) {
         if let Some((reference, _)) = self.raw {
           let mut value = ptr::null_mut();
diff --git a/crates/napi/src/bindgen_runtime/js_values/buffer.rs b/crates/napi/src/bindgen_runtime/js_values/buffer.rs
index 13cf98d3..4ef145a0 100644
--- a/crates/napi/src/bindgen_runtime/js_values/buffer.rs
+++ b/crates/napi/src/bindgen_runtime/js_values/buffer.rs
@@ -9,7 +9,7 @@ use std::sync::Arc;
 #[cfg(all(debug_assertions, not(windows)))]
 use std::sync::Mutex;
 
-#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_os = "wasi")))]
+#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_family = "wasm")))]
 use crate::bindgen_prelude::{CUSTOM_GC_TSFN, CUSTOM_GC_TSFN_DESTROYED, THREADS_CAN_ACCESS_ENV};
 use crate::{bindgen_prelude::*, check_status, sys, Result, ValueType};
 
@@ -37,7 +37,7 @@ impl Drop for Buffer {
         if ref_.is_null() {
           return;
         }
-        #[cfg(all(feature = "napi4", not(feature = "noop"), not(target_os = "wasi")))]
+        #[cfg(all(feature = "napi4", not(feature = "noop"), not(target_family = "wasm")))]
         {
           if CUSTOM_GC_TSFN_DESTROYED.load(std::sync::atomic::Ordering::SeqCst) {
             return;
diff --git a/crates/napi/src/bindgen_runtime/mod.rs b/crates/napi/src/bindgen_runtime/mod.rs
index 82dfb3ee..97605869 100644
--- a/crates/napi/src/bindgen_runtime/mod.rs
+++ b/crates/napi/src/bindgen_runtime/mod.rs
@@ -45,7 +45,7 @@ pub unsafe extern "C" fn raw_finalize_unchecked<T: ObjectFinalize>(
   {
     let finalize_callbacks_rc = unsafe { Rc::from_raw(finalize_callbacks_ptr) };
 
-    #[cfg(all(debug_assertions, not(target_os = "wasi")))]
+    #[cfg(all(debug_assertions, not(target_family = "wasm")))]
     {
       let rc_strong_count = Rc::strong_count(&finalize_callbacks_rc);
       // If `Rc` strong count is 2, it means the finalize of referenced `Object` is called before the `fn drop` of the `Reference`
diff --git a/crates/napi/src/bindgen_runtime/module_register.rs b/crates/napi/src/bindgen_runtime/module_register.rs
index d7542273..25f78a0f 100644
--- a/crates/napi/src/bindgen_runtime/module_register.rs
+++ b/crates/napi/src/bindgen_runtime/module_register.rs
@@ -3,10 +3,10 @@ use std::collections::HashMap;
 use std::collections::HashSet;
 use std::ffi::CStr;
 use std::ptr;
-#[cfg(all(feature = "napi4", not(target_os = "wasi")))]
+#[cfg(all(feature = "napi4", not(target_family = "wasm")))]
 use std::sync::atomic::AtomicPtr;
 #[cfg(all(
-  not(any(target_os = "macos", target_os = "wasi")),
+  not(any(target_os = "macos", target_family = "wasm")),
   feature = "napi4",
   feature = "tokio_rt"
 ))]
@@ -74,12 +74,12 @@ static IS_FIRST_MODULE: AtomicBool = AtomicBool::new(true);
 static FIRST_MODULE_REGISTERED: AtomicBool = AtomicBool::new(false);
 static REGISTERED_CLASSES: Lazy<RegisteredClassesMap> = Lazy::new(Default::default);
 static FN_REGISTER_MAP: Lazy<FnRegisterMap> = Lazy::new(Default::default);
-#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_os = "wasi")))]
+#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_family = "wasm")))]
 pub(crate) static CUSTOM_GC_TSFN: AtomicPtr<sys::napi_threadsafe_function__> =
   AtomicPtr::new(ptr::null_mut());
-#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_os = "wasi")))]
+#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_family = "wasm")))]
 pub(crate) static CUSTOM_GC_TSFN_DESTROYED: AtomicBool = AtomicBool::new(false);
-#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_os = "wasi")))]
+#[cfg(all(feature = "napi4", not(feature = "noop"), not(target_family = "wasm")))]
 // Store thread id of the thread that created the CustomGC ThreadsafeFunction.
 pub(crate) static THREADS_CAN_ACCESS_ENV: once_cell::sync::Lazy<
   PersistedPerInstanceHashMap<ThreadId, bool>,
@@ -251,7 +251,7 @@ fn load_host() {
   }
 }
 
-#[cfg(all(target_os = "wasi", not(feature = "noop")))]
+#[cfg(all(target_family = "wasm", not(feature = "noop")))]
 #[no_mangle]
 unsafe extern "C" fn napi_register_wasm_v1(
   env: sys::napi_env,
@@ -463,7 +463,7 @@ pub unsafe extern "C" fn napi_register_module_v1(
   }
 
   #[cfg(all(
-    not(any(target_os = "macos", target_os = "wasi")),
+    not(any(target_os = "macos", target_family = "wasm")),
     feature = "napi4",
     feature = "tokio_rt"
   ))]
@@ -482,7 +482,7 @@ pub unsafe extern "C" fn napi_register_module_v1(
       )
     };
   }
-  #[cfg(all(feature = "napi4", not(target_os = "wasi")))]
+  #[cfg(all(feature = "napi4", not(target_family = "wasm")))]
   create_custom_gc(env);
   FIRST_MODULE_REGISTERED.store(true, Ordering::SeqCst);
   exports
@@ -506,7 +506,7 @@ pub(crate) unsafe extern "C" fn noop(
   ptr::null_mut()
 }
 
-#[cfg(all(feature = "napi4", not(target_os = "wasi"), not(feature = "noop")))]
+#[cfg(all(feature = "napi4", not(target_family = "wasm"), not(feature = "noop")))]
 fn create_custom_gc(env: sys::napi_env) {
   use std::os::raw::c_char;
 
@@ -582,19 +582,19 @@ fn create_custom_gc(env: sys::napi_env) {
   );
 }
 
-#[cfg(all(feature = "napi4", not(target_os = "wasi"), not(feature = "noop")))]
+#[cfg(all(feature = "napi4", not(target_family = "wasm"), not(feature = "noop")))]
 unsafe extern "C" fn remove_thread_id(id: *mut std::ffi::c_void) {
   let thread_id = unsafe { Box::from_raw(id.cast::<ThreadId>()) };
   THREADS_CAN_ACCESS_ENV.borrow_mut(|m| m.insert(*thread_id, false));
 }
 
-#[cfg(all(feature = "napi4", not(target_os = "wasi"), not(feature = "noop")))]
+#[cfg(all(feature = "napi4", not(target_family = "wasm"), not(feature = "noop")))]
 #[allow(unused)]
 unsafe extern "C" fn empty(env: sys::napi_env, info: sys::napi_callback_info) -> sys::napi_value {
   ptr::null_mut()
 }
 
-#[cfg(all(feature = "napi4", not(target_os = "wasi"), not(feature = "noop")))]
+#[cfg(all(feature = "napi4", not(target_family = "wasm"), not(feature = "noop")))]
 #[allow(unused_variables)]
 unsafe extern "C" fn custom_gc_finalize(
   env: sys::napi_env,
@@ -604,7 +604,7 @@ unsafe extern "C" fn custom_gc_finalize(
   CUSTOM_GC_TSFN_DESTROYED.store(true, Ordering::SeqCst);
 }
 
-#[cfg(all(feature = "napi4", not(target_os = "wasi"), not(feature = "noop")))]
+#[cfg(all(feature = "napi4", not(target_family = "wasm"), not(feature = "noop")))]
 // recycle the ArrayBuffer/Buffer Reference if the ArrayBuffer/Buffer is not dropped on the main thread
 extern "C" fn custom_gc(
   env: sys::napi_env,
diff --git a/crates/napi/src/env.rs b/crates/napi/src/env.rs
index bbb1bb36..3e578be3 100644
--- a/crates/napi/src/env.rs
+++ b/crates/napi/src/env.rs
@@ -374,7 +374,7 @@ impl Env {
     ))
   }
 
-  #[cfg(not(target_os = "wasi"))]
+  #[cfg(not(target_family = "wasm"))]
   /// This function gives V8 an indication of the amount of externally allocated memory that is kept alive by JavaScript objects (i.e. a JavaScript object that points to its own memory allocated by a native module).
   ///
   /// Registering externally allocated memory will trigger global garbage collections more often than it would otherwise.
@@ -386,7 +386,7 @@ impl Env {
     Ok(changed)
   }
 
-  #[cfg(target_os = "wasi")]
+  #[cfg(target_family = "wasm")]
   #[allow(unused_variables)]
   pub fn adjust_external_memory(&mut self, size: i64) -> Result<i64> {
     Ok(0)
diff --git a/crates/napi/src/tokio_runtime.rs b/crates/napi/src/tokio_runtime.rs
index 02fc96d9..4728f6de 100644
--- a/crates/napi/src/tokio_runtime.rs
+++ b/crates/napi/src/tokio_runtime.rs
@@ -6,13 +6,13 @@ use tokio::runtime::Runtime;
 use crate::{sys, JsDeferred, JsUnknown, NapiValue, Result};
 
 fn create_runtime() -> Option<Runtime> {
-  #[cfg(not(target_os = "wasi"))]
+  #[cfg(not(target_family = "wasm"))]
   {
     let runtime = tokio::runtime::Runtime::new().expect("Create tokio runtime failed");
     Some(runtime)
   }
 
-  #[cfg(target_os = "wasi")]
+  #[cfg(target_family = "wasm")]
   {
     tokio::runtime::Builder::new_current_thread()
       .enable_all()
@@ -23,14 +23,14 @@ fn create_runtime() -> Option<Runtime> {
 
 pub(crate) static RT: Lazy<RwLock<Option<Runtime>>> = Lazy::new(|| RwLock::new(create_runtime()));
 
-#[cfg(not(any(target_os = "macos", target_os = "wasi")))]
+#[cfg(not(any(target_os = "macos", target_family = "wasm")))]
 static RT_REFERENCE_COUNT: std::sync::atomic::AtomicUsize = std::sync::atomic::AtomicUsize::new(0);
 
 /// Ensure that the Tokio runtime is initialized.
 /// In windows the Tokio runtime will be dropped when Node env exits.
 /// But in Electron renderer process, the Node env will exits and recreate when the window reloads.
 /// So we need to ensure that the Tokio runtime is initialized when the Node env is created.
-#[cfg(not(any(target_os = "macos", target_os = "wasi")))]
+#[cfg(not(any(target_os = "macos", target_family = "wasm")))]
 pub(crate) fn ensure_runtime() {
   use std::sync::atomic::Ordering;
 
@@ -42,7 +42,7 @@ pub(crate) fn ensure_runtime() {
   RT_REFERENCE_COUNT.fetch_add(1, Ordering::Relaxed);
 }
 
-#[cfg(not(any(target_os = "macos", target_os = "wasi")))]
+#[cfg(not(any(target_os = "macos", target_family = "wasm")))]
 pub(crate) unsafe extern "C" fn drop_runtime(_arg: *mut std::ffi::c_void) {
   use std::sync::atomic::Ordering;
 
@@ -140,10 +140,10 @@ pub fn execute_tokio_future<
     }
   };
 
-  #[cfg(not(target_os = "wasi"))]
+  #[cfg(not(target_family = "wasm"))]
   spawn(inner);
 
-  #[cfg(target_os = "wasi")]
+  #[cfg(target_family = "wasm")]
   {
     std::thread::spawn(|| {
       block_on(inner);
diff --git a/examples/napi/Cargo.toml b/examples/napi/Cargo.toml
index 4f4ad587..311e49a5 100644
--- a/examples/napi/Cargo.toml
+++ b/examples/napi/Cargo.toml
@@ -20,7 +20,7 @@ serde = "1"
 serde_derive = "1"
 serde_json = "1"
 
-[target.'cfg(not(target_os = "wasi"))'.dependencies]
+[target.'cfg(not(target_family = "wasm"))'.dependencies]
 napi = { path = "../../crates/napi", default-features = false, features = [
   "napi9",
   "serde-json",
@@ -36,7 +36,7 @@ napi = { path = "../../crates/napi", default-features = false, features = [
 ] }
 tokio = { version = "1", features = ["rt", "time"] }
 
-[target.'cfg(target_os = "wasi")'.dependencies]
+[target.'cfg(target_family = "wasm")'.dependencies]
 napi = { path = "../../crates/napi", default-features = false, features = [
   "napi9",
   "serde-json",
diff --git a/examples/napi/src/async.rs b/examples/napi/src/async.rs
index 724e3909..dde847fc 100644
--- a/examples/napi/src/async.rs
+++ b/examples/napi/src/async.rs
@@ -1,13 +1,13 @@
-#[cfg(not(target_os = "wasi"))]
+#[cfg(not(target_family = "wasm"))]
 use futures::prelude::*;
 use napi::bindgen_prelude::*;
 use napi::tokio;
-#[cfg(not(target_os = "wasi"))]
+#[cfg(not(target_family = "wasm"))]
 use napi::tokio::fs;
 
 #[napi]
 async fn read_file_async(path: String) -> Result<Buffer> {
-  #[cfg(not(target_os = "wasi"))]
+  #[cfg(not(target_family = "wasm"))]
   {
     fs::read(path)
       .map(|r| match r {
@@ -19,7 +19,7 @@ async fn read_file_async(path: String) -> Result<Buffer> {
       })
       .await
   }
-  #[cfg(target_os = "wasi")]
+  #[cfg(target_family = "wasm")]
   {
     let conetent = std::fs::read(path)?;
     Ok(conetent.into())